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CGP78850 

Cat. No.: HY-129800
Handling Instructions

CGP78850 is a potent and selective competitor of Grb2 SH2-phosphopeptide interactions. CGP78850 can be used for the research of cancer.

For research use only. We do not sell to patients.

CGP78850 Chemical Structure

CGP78850 Chemical Structure

CAS No. : 258326-83-9

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Description

CGP78850 is a potent and selective competitor of Grb2 SH2-phosphopeptide interactions. CGP78850 can be used for the research of cancer[1].

IC50 & Target

Grb2 SH2-phosphopeptide[1]

In Vitro

CGP78850 (0~100 μM; 90 minutes; MDA-MB-468 cells) reduces the amount of associated Grb2 protein in a dose-dependent manner[1].
CGP78850 blocks epidermal growth factor receptor (EGFR)-Grb2 and Shc-Grb2 interaction in living cells. CGP78850 inhibits MDA-MB-468 cells to form colonies in soft agar in a dose-dependent manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: MDA-MB-468 cells
Concentration: 0~100 μM
Incubation Time: 90 minutes
Result: Reduced the amount of associated Grb2 protein in a dose-dependent manner.
Molecular Weight

723.75

Formula

C₃₆H₄₆N₅O₉P

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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CGP78850
Cat. No.:
HY-129800
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