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Cat. No.: HY-101049

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CGS 12066 dimaleate

Name: CGS 12066 dimaleate
Brand: MedChemExpress
SKU: HY-101049
Price: 132.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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CGS 12066 (dimaleate) dimaleate is a selective 5-HT_1B receptor agonist with an IC₅₀ of 51 nM.

For research use only. We do not sell to patients.

CAS No.: 109028-10-6
Formula: C₂₅H₂₅F₃N₄O₈
Molecular Weight:566.48

Storage:

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

CGS 12066 dimaleate Chemical Structure

CAS No.: 109028-10-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

CGS 12066 (dimaleate) dimaleate is a selective 5-HT_1B receptor agonist with an IC₅₀ of 51 nM^[1].

IC₅₀ & Target

5-HT_1B Receptor

51 nM (IC₅₀)

All 5-HT Receptor Isoforms :

Chemical Information

CAS No. 109028-10-6
Appearance Solid
Molecular Weight 566.48
Formula C₂₅H₂₅F₃N₄O₈
Color White to off-white
SMILES

FC(C1=CC2=C(N3C(C(N4CCN(C)CC4)=N2)=CC=C3)C=C1)(F)F.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Neale RF, et al. Biochemical and pharmacological characterization of CGS 12066B, a selective serotonin-1B agonist. Eur J Pharmacol. 1987 Apr 7;136(1):1-9. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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