Asperindole A
Asperindole A is an indole-diterpene alkaloid. Asperindole A can be isolated from fungus Aspergillus sp. KMM 4676. Asperindole A induces Apoptosis. Asperindole A exerts cytotoxic activity against hormone-resistant and hormone-sensitive prostate cancer cells.
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- CAS. Nr.: 2416222-17-6
- Formel: C29H32ClNO6
- Molecular Weight:526.02
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
Fungal Metabolite |
In Vitro
Asperindole A potently reduces viability of PC-3, LNCaP, and 22Rv1 human prostate cancer cells with IC50 values of 69.4 μM, 47.8 μM, and 4.86 μM, respectively[1].
Asperindole A (0.3125-5 μM; 48 h) induces concentration-dependent apoptosis in 22Rv1 human prostate cancer cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2416222-17-6
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Molecular Weight 526.02
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Formel C29H32ClNO6
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SMILES
O[C@]12C([C@@]3(CC[C@@]1([C@]4(C5=C(C6=CC=C(Cl)C=C6N5)C[C@]4([H])CC2)C)C)O[C@]7([H])[C@](C)(CO3)OC(C)=O)=CC7=O
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Structure Classification
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Initial Source
Aspergillus sp.
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
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Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Asperindole A Related Classifications
HY-N16404 Related Classifications
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