country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Art. -Nr.: HY-183553

Copy Link Print Information

AUBE00

AUBE00 is an orally active, selective cyclic peptide pan-KRAS inhibitor. AUBE00 selectively binds to the OFF state of KRAS. AUBE00 exhibits anticancer activity against RAS wild-type colorectal cancer. The combination of AUBE00 with Cetuximab (HY-P9905) produces a synergistic antiproliferative effect.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 2874214-01-2
Formel: C₇₈H₁₁₀F₆N₁₂O₁₄
Molecular Weight:1553.77

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

AUBE00 Chemical Structure

CAS. Nr.: 2874214-01-2

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]

K-RAS

Alle Ras Isoform-spezifische Produkte anzeigen :

In Vitro

AUBE00 exhibits potent antiproliferative activity against cancer cell lines harboring various KRAS mutations^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2874214-01-2
Molecular Weight 1553.77
Formel C₇₈H₁₁₀F₆N₁₂O₁₄
SMILES

CN1C2(CCC2)C(N([C@@H](C3CCCC3)C(N([C@@H](CC(N([C@H](C(N[C@@](C(N4[C@](CCC4)([H])C(N([C@]5([H])C(N(CC/C=C\C5)[C@H](C(N(CC(N[C@H](C(N6[C@](C[C@H](C6)OCC)([H])C1=O)=O)CCC7=CC(OC)=C(C=C7)C(F)(F)F)=O)C)=O)CC8=CC=C(C=C8)C(F)(F)F)=O)C)=O)=O)([H])[C@@H](C)CC)=O)CCC)C)=O)C(N(C)C)=O)C)=O)C)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Takei K, et al. AUBE00: A novel cyclic peptide pan-KRAS inhibitor targeting KRAS-activated cancers including KRAS-mutant cancers and wild-type colorectal cancer[J]. Cancer Research, 2026, 86(7_Supplement): 5980-5980.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Angebot einholen Auf Lager

Other size

Angebot einholen

Amount: USD 0.00

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise

Produktname:
Art. -Nr.:
Menge:
MCE Japan Authorized Agent:

Produktname:
CAS. Nr.:
Species:
Reinheit:
Menge:

AUBE00

Alle Ras Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

AUBE00 Related Classifications

HY-183553 Related Classifications