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Art. -Nr.: HY-117385

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CGP-33304 sodium

CGP-33304 sodium is an antagonist of the leukotriene receptor and an inhibitor of phospholipase A₂. CGP-33304 sodium inhibits the accumulation of myocardial depressant factor (MDF) activity in plasma and prolongs survival time in a standardized traumatic shock model of rats. CGP-33304 sodium can be applied in the research of traumatic shock.

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CAS. Nr.: 111130-14-4
Formel: C₂₃H₂₅BrN₅NaO₅
Molecular Weight:554.37

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Please store the product under the recommended conditions in the Certificate of Analysis.

CGP-33304 sodium Chemical Structure

CAS. Nr.: 111130-14-4

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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^[1]

PLA2

Alle Leukotriene Receptor Isoform-spezifische Produkte anzeigen :

Alle Phospholipase Isoform-spezifische Produkte anzeigen :

In Vivo

CGP-33304 sodium inhibits the accumulation of MDF activity in plasma, prolongs survival time, exhibits significant antiproteolytic activity, and prevents leukotriene-induced hypoxia secondary to bronchoconstriction under shock conditions in a standardized traumatic shock rat model (subjected to Noble-Collip drum trauma) ^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 111130-14-4
Molecular Weight 554.37
Formel C₂₃H₂₅BrN₅NaO₅
SMILES

O=C(C1=NNN=N1)NC2=CC(OCCCOC3=CC=C(C(C)=O)C(O[Na])=C3CCC)=C(Br)C=C2C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Masamune, Hiroko et al. Novel Applications of leukotriene intervention. Annual Reports in Medicinal Chemistry. Vol. 24. Academic Press, 1989. 71-79.

[2]. Levitt, M. A., et al. Efficacy of two leukotriene antagonists in rat traumatic shock. Methods and Findings in Experimental and Clinical Pharmacology 9.5 (1987): 269-273.

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Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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CGP-33304 sodium

Alle Leukotriene Receptor Isoform-spezifische Produkte anzeigen

Alle Phospholipase Isoform-spezifische Produkte anzeigen

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