Drimentine C
Drimentine C is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria. It inhibits proliferation of NS-1 murine β lymphocyte myeloma cells by 63 and 98% in vitro when used at concentrations of 12.5 and 100 μg/mL, respectively.
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- CAS. Nr.: 204398-92-5
- Formel: C31H41N3O2
- Molecular Weight:487.68
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
>10 μM
Compound: 4
|
Cytotoxicity against human A2780 cells by MTT assay
Cytotoxicity against human A2780 cells by MTT assay
|
[PMID: 23547884] |
| A549 | IC50 |
>10 μM
Compound: 4
|
Cytotoxicity against human A549 cells by MTT assay
Cytotoxicity against human A549 cells by MTT assay
|
[PMID: 23547884] |
| Bel-7402 | IC50 |
>10 μM
Compound: 4
|
Cytotoxicity against human Bel7402 cells by MTT assay
Cytotoxicity against human Bel7402 cells by MTT assay
|
[PMID: 23547884] |
| BGC-823 | IC50 |
>10 μM
Compound: 4
|
Cytotoxicity against human BGC823 cells by MTT assay
Cytotoxicity against human BGC823 cells by MTT assay
|
[PMID: 23547884] |
| HCT-8 | IC50 |
>10 μM
Compound: 4
|
Cytotoxicity against human HCT8 cells by MTT assay
Cytotoxicity against human HCT8 cells by MTT assay
|
[PMID: 23547884] |
Chemical Information
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CAS. Nr. 204398-92-5
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Molecular Weight 487.68
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Formel C31H41N3O2
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SMILES
O=C(N1CCC[C@]1(C2=O)[H])[C@]3(N2[C@]4([C@@](C[C@]5(C(CC[C@@]6([C@@]5(CCCC6(C)C)C)[H])=C)[H])(C3)C7=C(N4)C=CC=C7)[H])[H]
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)