Art. -Nr.: HY-128868

FITC-Dextran (MW 10000)

98 Cited Publications

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Based on 98 publication(s) in Google Scholar

FITC-Dextran (MW 10000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 10000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 10000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption.

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CAS. Nr.: 60842-46-8
Molecular Weight:10000.00(Average)

Speicherung:

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

FITC-Dextran (MW 10000) Chemical Structure

CAS. Nr.: 60842-46-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
- In Vivo
- Emission (Em)
- Excitation (Ex)
- Dyeing Example
Chemical Information
Publications (98)
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

Guide (The following is our recommended protocol. This protocol is only a guide and should be modified according to your specific needs).
1. Cell Marking (for cells undergoing apoptosis)^[1]:
1.1 Resuspend cells in culture medium and add Propidium Iodide (PI) and FITC-Dextran to a final concentration of 7.5 μM and 1.13 μM, respectively.
1.2 Incubate cells at room temperature in the dark for 25 minutes.
1.3 Centrifuge at 500 g for 10 minutes and discard the supernatant.
1.4 Resuspend cells in culture medium and analyze using flow cytometry or fluorescence microscopy (PI: Ex=500 nm, Em=600 nm; FITC-Dextran: Ex=495 nm, Em=525 nm).
2. Side-cell permeability assay^[4]
2.1 Add FITC-Dextran (0.1 mg/mL) to the basal medium in the upper chamber of the transwell.
2.2 Collect the medium from the lower chamber of the transwell after 15 minutes.
2.3 Measure the fluorescence signal (Ex=495 nm, Em=525 nm).
2.4 Calculate the FITC-Dextran concentration based on the fluorescence intensity.
2.5 Calculate the permeability.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).
For intestinal barrier function assay^[5]
1. Fast mice for 4 h.
2. Orally gavage mice with FITC-Dextran MW 10000 (0.6 mg/g).
3. Measure fluorescence intensity of plasma in 4 h (excitation nm/emission 520 nm).

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Emission (Em)

525

Excitation (Ex)

488

Dyeing Example

Chemical Information

CAS. Nr. 60842-46-8
Appearance Solid
Molecular Weight 10000.00(Average)
Color Yellow to brown
SMILES

[FITC-Dextran (MW 10000)]
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Publications (98)

All Bio/Physico-chemical AssayIn Vivo Efficacy StudyIn Vivo Imaging

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Journal Impact Factor

Signal Transduct Target Ther

Oligomeric cystatin C supports the immunosuppressive activity of myeloid cells through interaction with inhibitory receptors. [Abstract]

2025 Nov 14;10(1):368. PMID: 41233352
Nat Metab

Combined alcohol and cannabinoid exposure leads to synergistic toxicity by affecting cerebellar Purkinje cells. [Abstract]

2022 Sep;4(9):1138-1149. PMID: 36109623
Nat Commun

Endothelial leakiness elicited by amyloid protein aggregation. [Abstract]

2024 Jan 19;15(1):613. PMID: 38242873
ACS Nano

Central Nervous System Targeting Nanovesicles for Trans-Barrier Delivery and Spinal Cord Injury Treatment. [Abstract]

2025 Dec 19. PMID: 41420148
Gut Microbes

Dietary conjugated linoleic acid enhances resistance to Salmonella infection by promoting PPARγ-mediated metabolic reprogramming and effector function in CD8⁺ T cells. [Abstract]

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Gut microbiota metabolite indole-3-acetic acid maintains intestinal epithelial homeostasis through mucin sulfation. [Abstract]

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J Nanobiotechnology

Exosome-shuttled miR-5121 from A2 astrocytes promotes BSCB repair after traumatic SCI by activating autophagy in vascular endothelial cells. [Abstract]

2025 Apr 15;23(1):291. PMID: 40229869

FITC-Dextran (MW 10000) purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2025 Apr 15;23(1):291. [Abstract]

FITC-dextran (1 mg/mL; 45 min) permeability assay was performed to assess the barrier function of bEnd.3 endothelial cells.
Adv Sci (Weinh)

Intestinal Epithelial-Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78-mediated Endoplasmic Reticulum Stress. [Abstract]

2025 Jul 18:e00741. PMID: 40679368

FITC-Dextran (MW 10000) purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jul 18:e00741. [Abstract]

Intestinal permeability was assessed by FITC‐Dextran (0.6 mg/g; Oral gavage) assays on day 10 after DSS initiation (n = 6).
Adv Sci (Weinh)

ACSS2-Mediated Histone H4 Lysine 12 Crotonylation (H4K12cr) Alleviates Colitis via Enhancing Transcription of CLDN7. [Abstract]

2025 Aug;12(30):e00461. PMID: 40650658
Adv Sci (Weinh)

Single-Cell Multi-omics Assessment of Spinal Cord Injury Blocking via Cerium-doped Upconversion Antioxidant Nanoenzymes. [Abstract]

2025 Jan 9:e2412526. PMID: 39783786
Adv Sci (Weinh)

Erythrocytes, a New Contributor to Age-Associated Loss of Blood-Brain Barrier Integrity. [Abstract]

2021 Oct;8(20):e2101912. PMID: 34396716

FITC-Dextran (MW 10000) purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2021 Oct;8(20):e2101912. [Abstract]

Large particle transport assays through µE‐BBB were conducted by passing of FITC‐dextran (100 µg/mL; 1 h) solution through the lumen compartment of the system and quantifying the amount of FITC‐dextran that had accumulated in the basolateral compartment.

FITC-Dextran (MW 10000) purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2021 Oct;8(20):e2101912. [Abstract]

To evaluate the effect of erythrocytes on the permeability of the BBB, isolated erythrocytes from young or old mice, supplemented with FITC‐dextran (100 μg/mL; 1 h), were circulated through the µE‐BBB.
Sci Adv

Neurological disorders after severe pneumonia are associated with translocation of endogenous bacteria from the lung to the brain. [Abstract]

2023 Oct 20;9(42):eadi0699. PMID: 37851811

FITC-Dextran (MW 10000) purchased from MedChemExpress. Usage Cited in: Sci Adv. 2023 Oct 20;9(42):eadi0699. [Abstract]

Ex vivo imaging showed biodistribution of FITC-Dextran (MW 4000) (500 μg/mouse; i.v.; Single dose).
Biomaterials

Targeted liposomes for combined delivery of artesunate and temozolomide to resistant glioblastoma. [Abstract]

2022 Aug:287:121608. PMID: 35690021
Brain

NINJ1 hypomethylation enhances endothelial dysfunction in brain arteriovenous malformations. [Abstract]

2026 May 26:awag189. PMID: 42189175
Pharmacol Res

Multi-omics approaches for the understanding of therapeutic mechanism for Huang-Qi-Long-Dan Granule against ischemic stroke. [Abstract]

2024 May 21:205:107229. PMID: 38782148
Cancer Lett

Spatiotemporal characteristics of tissue derived small extracellular vesicles is associated with tumor relapse and anti-PD-1 response. [Abstract]

2024 Jun 1:591:216897. PMID: 38631664

FITC-Dextran (MW 10000) purchased from MedChemExpress. Usage Cited in: Cancer Lett. 2024 Jun 1:591:216897. [Abstract]

Fluorescence intensity of FITC-dextran (500 μg/mL; 36 h) in lower chamber of Transwell after incubation with TM-sEVs from patients with low relapse risk and high relapse risk in the upper chamber.
Cell Commun Signal

Enhancing intestinal epithelial microtubule stability could alleviate IBD symptoms. [Abstract]

2025 Jun 4;23(1):263. PMID: 40462136

FITC-Dextran (MW 10000) purchased from MedChemExpress. Usage Cited in: Cell Commun Signal. 2025 Jun 4;23(1):263. [Abstract]

Quantitative analysis of FITC in serum collected from mice in the FITC-Dextran (MW 4000) (0.6 mg/g; Oral gavage; Single dose) intestinal permeability assay.
Phytomedicine

Alpha-linolenic acid improves nasal mucosa epithelial barrier function in allergic rhinitis by arresting CD4+ T cell differentiation via IL-4Rα-JAK2-STAT3 pathway. [Abstract]

2023 Jul 25:116:154825. PMID: 37178572
EBioMedicine

Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury. [Abstract]

2022 Aug:82:104181. PMID: 35908416
Mater Today Bio

EUK nanozyme-loaded PL&GA coacervate droplets attenuate ulcerative colitis through restoring gut homeostasis and restricting intestinal cell ferroptosis. [Abstract]

2025 Oct 25:35:102466. PMID: 41215769
Acta Pharmacol Sin

Activation of MST1 protects filtration barrier integrity of diabetic kidney disease in mice through restoring the tight junctions of glomerular endothelial cells. [Abstract]

2025 May;46(5):1345-1360. PMID: 39643641
NPJ Sci Food

Long-term sucralose exposure accelerates ovarian aging via gut microbiota dysbiosis. [Abstract]

2026 Mar 24. PMID: 41876529
J Transl Med

S1PR3 inhibition protects against LPS-induced ARDS by inhibiting NF-κB and improving mitochondrial oxidative phosphorylation. [Abstract]

2024 Jun 5;22(1):535. PMID: 38840216
Sci China Life Sci

Downregulation of METTL3 enhances TRADD-mediated apoptosis in inflammatory bowel disease. [Abstract]

2025 Jul;68(7):2010-2027. PMID: 40347213

FITC-Dextran (MW 10000) purchased from MedChemExpress. Usage Cited in: Sci China Life Sci. 2025 Jul;68(7):2010-2027. [Abstract]

Blood FITC-Dextran (MW 4000) (200 mg/kg; Oral gavage; Single dose) levels. The results showed that METTL3-deficient mice presented significantly increased serum FITC levels, indicating increased mucosal permeability.
Int J Biol Macromol

Alginate-gelatin hydrogel scaffolds for establishing physiological barriers on a gut-brain-axis microchip. [Abstract]

2025 May 9:144084. PMID: 40350126

FITC-Dextran (MW 10000) purchased from MedChemExpress. Usage Cited in: Int J Biol Macromol. 2025 May 9:144084. [Abstract]

MFI variations with time in Ch1, Ch3 and Ch5 of 10 kDa FITC-dextran (0.1 mg/mL; 0-24 h) diffusion.
Device

2024 June 12
Clin Transl Med

Mechanism of Gzma-mediated GEF-H1 activation in intestinal epithelial cells leading to intestinal barrier dysfunction in sepsis. [Abstract]

2026 Apr;16(4):e70651. PMID: 41943423
ACS Appl Mater Interfaces

Programmable Nanoarchitectonics for Artificial Cells via Coupled Multidimensional Regulation of Phase State and Multiscale Transport Dynamics. [Abstract]

2026 Jun 17;18(23):32406-32418. PMID: 42258394
Cell Rep

Extensive jejunal injury is repaired by migration and transdifferentiation of ileal enterocytes in zebrafish. [Abstract]

2023 Jun 20;42(7):112660. PMID: 37342912
Cell Rep

Oral feeding of nanoplastics affects brain function of mice by inducing macrophage IL-1 signal in the intestine. [Abstract]

2023 Apr 4;42(4):112346. PMID: 37022934
Brain Behav Immun

Targeting α7nAChR-driven brain endothelial pyroptosis mitigates HIV-1 gp120-induced blood-brain barrier breakdown. [Abstract]

2026 May:134:106478. PMID: 41651130
Brain Behav Immun

Dietary fish oil improves autistic behaviors and gut homeostasis by altering the gut microbial composition in a mouse model of fragile X syndrome. [Abstract]

2023 May:110:140-151. PMID: 36858183
Int J Radiat Oncol Biol Phys

Activation of Angiotensin Converting Enzyme 2 (ACE2) Mitigates Gastrointestinal Acute Radiation Syndrome (GI-ARS). [Abstract]

2025 Sep 16:S0360-3016(25)06272-8. PMID: 40967372
Redox Rep

Sodium formate induces development-dependent intestinal epithelial injury via necroptosis and apoptosis. [Abstract]

2024 Dec;29(1):2433393. PMID: 39620924

FITC-Dextran (MW 10000) purchased from MedChemExpress. Usage Cited in: Redox Rep. 2024 Dec;29(1):2433393. [Abstract]

Intestinal permeability measured by serum fluorescein isothiocyanate FITC-Dextran (MW 4000) (0.44 mg/g; Oral gavage; Single dose) levels.
J Ethnopharmacol

Chebulinic acid shields Villin 1 from covalent attack to mitigate Euphorbia fischeriana enterotoxicity: A basis for safer anti-ascites therapy. [Abstract]

2025 Aug 18;353(Pt B):120435. PMID: 40835194
J Ethnopharmacol

Glycine tabacina extract alleviates inflammatory bowel disease via NF-κB, JNK and Nrf2 signaling pathways. [Abstract]

2025 Apr 6:119744. PMID: 40199409
J Ethnopharmacol

Magnolol preserves the integrity of the intestinal epithelial barrier and mitigates intestinal injury through activation of PPAR γ in COPD rat. [Abstract]

2024 Nov 9;338(Pt 2):119068. PMID: 39522848
J Ethnopharmacol

Dachaihu decoction alleviates septic intestinal epithelial barrier disruption via PI3K/AKT pathway based on transcriptomics and network pharmacology. [Abstract]

2024 Oct 16;337(Pt 3):118937. PMID: 39419306
J Ethnopharmacol

Shexiang Tongxin dropping pills protect against ischemic stroke-induced cerebral microvascular dysfunction via suppressing TXNIP/NLRP3 signaling pathway. [Abstract]

2024 Mar 25:322:117567. PMID: 38122909
J Ethnopharmacol

Xihuang pill ameliorates colitis in mice by improving mucosal barrier injury and inhibiting inflammatory cell filtration through network regulation. [Abstract]

2024 Jan 30;319(Pt 1):117098. PMID: 37640256
Ecotoxicol Environ Saf

Mechanisms of colon toxicity induced by long-term perfluorooctanoic acid exposure in mice. [Abstract]

2024 Jul 23:282:116762. PMID: 39047366
Food Front

2026 May 28;7(4):e70301.
Food Funct

Procyanidin A1 and its digestive products prevent acrylamide-induced intestinal barrier dysfunction via the MAPK-mediated MLCK pathway. [Abstract]

2021 Nov 29;12(23):11956-11965. PMID: 34747428
Adv Mater Technol

2026 Jun 17.
Colloids Surf B Biointerfaces

Design and mechanistic evaluation of charge-converting fusogenic liposomes for efficient nucleic acid delivery. [Abstract]

2026 Sep:265:115744. PMID: 42068612
Int J Mol Sci

Berberine Alleviates Intestinal Inflammation by Disrupting Pathological Macrophage-Epithelial Crosstalk in Macrophage-Organoid Co-Culture Model. [Abstract]

2025 Oct 19;26(20):10161. PMID: 41155453
Int Immunopharmacol

House dust mite induced mucosal barrier dysfunction and type 2 inflammatory responses via the MAPK/AP-1/IL-24 Signaling pathway in allergic rhinitis. [Abstract]

2025 Jan 17:148:113972. PMID: 39826453
Int Immunopharmacol

Geranylgeranylacetone mitigates sepsis-associated intestinal injury through CHIP-dependent anti-inflammation and anti-oxidative effect. [Abstract]

2024 May 23:135:112263. PMID: 38788444
Mol Neurobiol

Embryonic 6:2 Fluorotelomer Alcohol Exposure Disrupts the Blood‒Brain Barrier by Causing Endothelial‒to‒Mesenchymal Transition in the Male Mice. [Abstract]

2025 Apr;62(4):4203-4220. PMID: 39417922
Mucosal Immunol

Dysregulated NOX1-NOS2 activity as hallmark of ileitis in mice. [Abstract]

2024 Sep 6:S1933-0219(24)00093-X. PMID: 39245144
mBio

ATP1A1 enhances porcine reproductive and respiratory syndrome virus type 2 attachment and internalization. [Abstract]

2026 Apr 8;17(4):e0389625. PMID: 41773865
Front Pharmacol

Exploration of the mechanism of Taohong Siwu Decoction for the treatment of ischemic stroke based on CCL2/CCR2 axis. [Abstract]

2024 Aug 29:15:1428572. PMID: 39268469
Front Pharmacol

Chinese Herbal Preparation SaiLuoTong Alleviates Brain Ischemia via Nrf2 Antioxidation Pathway-Dependent Cerebral Microvascular Protection. [Abstract]

2021 Nov 2:12:748568. PMID: 34795584
Probiotics Antimicrob Proteins

Potential Benefits of Metformin Via Roseburia Intestinalis in High-fat Diet-fed Mice With Colorectal Adenomas. [Abstract]

2025 Nov 26. PMID: 41296177
Mol Med Rep

Octreotide attenuates intestinal barrier damage by maintaining basal autophagy in Caco2 cells. [Abstract]

2024 Jun;29(6):90. PMID: 38577927
PLoS Pathog

Manganese is a potent inducer of lysosomal activity that inhibits de novo HBV infection. [Abstract]

2025 Jan 2;21(1):e1012800. PMID: 39746094
FEBS J

LC3-positive extracellular vesicles released from tumor cells promote lung metastasis of breast cancer by inducing vascular permeability. [Abstract]

2025 Nov 27. PMID: 41307630
FEBS J

A high cholesterol diet aggravates experimental colitis through SREBP2-modulated endocytosis and degradation of occludin and Zo-1 proteins. [Abstract]

2025 Mar;292(5):1052-1069. PMID: 39279038
Curr Issues Mol Biol

The Nocardia Rubra Cell Wall Skeleton Regulates Macrophages and Promotes Wound Healing. [Abstract]

2022 Nov 29;44(12):5995-6005. PMID: 36547069
Naunyn Schmiedebergs Arch Pharmacol

Asiaticoside alleviates inflammation and intestinal barrier dysfunction in Crohn's disease-like colitis in a manner associated with the RhoA/ROCK/MLC pathway. [Abstract]

2026 May 16. PMID: 42142140
J Funct Foods

2024 Nov.
J Tradit Complement Med

Tianqi pingchan granule promotes recovery of glymphatic system function in a rat model of l-DOPA-induced dyskinesia. [Abstract]

2024 Apr 29;15(4):380-387. PMID: 40677540
Neurotox Res

Pramipexole Protects Against Traumatic Brain Injury-Induced Blood-Brain Barrier (BBB) Dysfunction. [Abstract]

2022 Aug;40(4):1020-1028. PMID: 35524855
J Neurotrauma

Clostridium butyricum Restores Intestinal Barrier Integrity via the IL-22/Reg3 Pathway Following Traumatic Brain Injury in Mice. [Abstract]

2025 Aug 29. PMID: 40879524
Immun Inflamm Dis

Neohesperidin Dihydrochalcone Alleviates Lipopolysaccharide-Induced Vascular Endothelium Dysfunction by Regulating Antioxidant Capacity. [Abstract]

2024 Dec;12(12):e70107. PMID: 39699295
Immun Inflamm Dis

Inhibiting P2Y12 receptor relieves LPS-induced inflammation and endothelial dysfunction. [Abstract]

2022 Oct;10(10):e697. PMID: 36169256
Biochem Biophys Rep

HMGB1 impairs nasal mucosa epithelial barrier function in allergic rhinitis by promoting BECN1-mediating autophagy. [Abstract]

2025 Nov 11:44:102351. PMID: 41311371
BMC Infect Dis

Alleviating penicillin-resistant Streptococcus pneumoniae‑induced lung epithelial cell injury: mechanistic insights into effects of the optimized combination of main components from Yinhuapinggan granules. [Abstract]

2025 Apr 20;25(1):565. PMID: 40254610
Kaohsiung J Med Sci

HMGB1 inhibition blocks ferroptosis and oxidative stress to ameliorate sepsis-induced acute lung injury by activating the Nrf2 pathway. [Abstract]

2024 Aug;40(8):710-721. PMID: 38837857
J Steroid Biochem Mol Biol

A vitamin D deficient diet increases weight gain and compromises bone biomechanical properties without a reduction in BMD in adult female mice. [Abstract]

2023 Jul:231:106314. PMID: 37088440
Immunobiology

Monocyte-derived immature dendritic cells negatively regulate hepatic stellate cells in vitro by secreting IL-10. [Abstract]

2023 Mar;228(2):152315. PMID: 36608595
Cell Tissue Res

Endothelial cells induce degradation of ECM through enhanced secretion of MMP14 carried on extracellular vesicles in venous malformation. [Abstract]

2022 Sep;389(3):517-530. PMID: 35786766
Vet Microbiol

Disruption of goat airway epithelial barrier function by caprine parainfluenza virus type 3 infection in an ALI model. [Abstract]

2026 Mar:314:110900. PMID: 41576713
Int J Hyperthermia

Activation of the liver X receptor α protects the blood-brain barrier against heatstroke-induced injury. [Abstract]

2025 Dec;42(1):2559022. PMID: 40954981
Prev Nutr Food Sci

Protective Effects of Peanut Sprouts from a Smart Farming System on the Barrier Function of Human Epithelial Cells. [Abstract]

2024 Dec 31;29(4):474-484. PMID: 39759809
Biochem Biophys Res Commun

DANCR maintained colon epithelial homeostasis by regulating the TNFα/NF-κB pathway. [Abstract]

2024 Sep 3:723:150176. PMID: 38820627
Biochem Biophys Res Commun

ACE2 contributes to the maintenance of mouse epithelial barrier function. [Abstract]

2020 Dec 17;533(4):1276-1282. PMID: 33097186
Exp Ther Med

Atorvastatin ameliorates chronic subdural hematomas by interrupting the 'chronic subdural hematoma cycle' via inhibition of the inflammatory response. [Abstract]

2025 Nov 14;31(1):22. PMID: 41367709
Exp Brain Res

Improvement of cerebral ischemia-reperfusion injury by L-3-n-butylphthalide through promoting angiogenesis. [Abstract]

2021 Jan;239(1):341-350. PMID: 33180154
Eur J Histochem

Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway. [Abstract]

2025 Jan 21;69(1). PMID: 39836101
J Vis Exp

Optimized Intravenous Injection in Adult Zebrafish. [Abstract]

2024 Dec 20:(214). PMID: 39760378
medRxiv

2026 Feb 19.
Res Sq

2026 Jan 19.
Res Sq

2025 Dec 15.
iMetaOmics

2025 Aug 06.
bioRxiv

2025 May 11.
SSRN

2025 May 21.
SSRN

2025 Mar 11.
Res Sq

2024 Aug 13.
Biomed Pharmacother

YL-109 attenuates sepsis-associated multiple organ injury through inhibiting the ERK/AP-1 axis and pyroptosis by upregulating CHIP. [Abstract]

2024 Jun:175:116633. PMID: 38670049
Research Square Preprint

2024 Apr 9.
Research Square Preprint

2023 Oct 10.
Research Square Preprint

2023 Oct 23.
Heliyon

miR-185-5p / ATG101 axis alleviated intestinal barrier damage in intestinal ischemia reperfusion through autophagy. [Abstract]

2023 Jul 16;9(7):e18325. PMID: 37539299
SSRN

2023 Jun 12.
Research Square Print

2023 Feb 23.
Bioengineered

The protective effects of butorphanol tartrate against homocysteine-induced blood-brain barrier dysfunction. [Abstract]

2022 Mar;13(3):7209-7220. PMID: 35245993
Bioengineered

The protective effects of Mirtazapine against lipopolysaccharide (LPS)-induced brain vascular hyperpermeability. [Abstract]

2022 Feb;13(2):3680-3693. PMID: 35081868

Lösungsmittel & Löslichkeit

In Vitro:

H₂O : 50 mg/mL (Need ultrasonic)

View the Complete Stock Solution Preparation Table

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (280 KB)
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Moumaris M, et al. Fluorescein isothiocyanate-dextran can track apoptosis and necrosis induced by heat shock of peripheral blood mononuclear cells and HeLa cells[J]. Open Biological Sciences Journal, 2015, 1(1).

[2]. Natarajan R, et al. Fluorescein Isothiocyanate (FITC)-Dextran Extravasation as a Measure of Blood-Brain Barrier Permeability. Curr Protoc Neurosci. 2017 Apr 10;79:9.58.1-9.58.15. [Content Brief]

[3]. Eriksson I, et al. Analysis of Lysosomal pH by Flow Cytometry Using FITC-Dextran Loaded Cells. Methods Mol Biol. 2017;1594:179-189. [Content Brief]

[4]. Okabayashi K, et al. Cdc42 activates paracellular transport in polarised submandibular gland cells. Arch Oral Biol. 2021 Dec;132:105276. [Content Brief]

[5]. Yu W, et al. ACE2 contributes to the maintenance of mouse epithelial barrier function. Biochem Biophys Res Commun. 2020 Dec 17;533(4):1276-1282. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

FITC-Dextran (MW 10000)

98 Cited Publications

100 mg Angebot einholen

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FITC-Dextran (MW 10000)

Publications Citing Use of MedChemExpress (MCE) FITC-Dextran (MW 10000)

Biologische Aktivität

Chemical Information

Publications (98)

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

FITC-Dextran (MW 10000) Related Classifications

HY-128868 Related Classifications