LEMD1 - LEM domain containing 1 Gene

Also Known as CT50; LEMP-1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 93273

About LEMD1

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:205,381,378-205,449,966 (from NCBI)

This gene has 8 transcripts (splice variants), 145 orthologues and 1 paralogue. Restricted expression toward testis (RPKM 16.5).

Summary

Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

LEMD1 Products (4)

mRNA Protein Name
NM_001001552.5 NP_001001552.3 LEM domain-containing protein 1 isoform 3
NM_001199050.2 NP_001185979.1 LEM domain-containing protein 1 isoform 1
NM_001199051.2 NP_001185980.1 LEM domain-containing protein 1 isoform 2
NM_001199052.2 NP_001185981.1 LEM domain-containing protein 1 isoform 4

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LEMD1 Protein Structure

LEM

LEM: LEM domain (2 - 27)

  • 0
  • 100
  • 140 a.a.
Protein Preferred Names Protein Names

LEM domain-containing protein 1

  • LEM domain protein 1

LEMD1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
LEMD1 Q68G75 RETREG3 Homo sapiens Q86VR2
Y2H Array
32296183
Intra
LEMD1 Q68G75 RETREG3 Homo sapiens Q86VR2
Y2H Prey Pooling
32296183
Intra
LEMD1 Q68G75 RETREG3 Homo sapiens Q86VR2
Validated Y2H
32296183
Intra
LEMD1 Q68G75 JAGN1 Homo sapiens Q8N5M9
Validated Y2H
32296183
Intra
LEMD1 Q68G75 JAGN1 Homo sapiens Q8N5M9
Y2H Array
32296183
Intra
LEMD1 Q68G75 JAGN1 Homo sapiens Q8N5M9
Y2H Prey Pooling
32296183
Intra
LEMD1 Q68G75 TMPPE Homo sapiens Q6ZT21
Y2H Array
32296183
Intra
LEMD1 Q68G75 TMPPE Homo sapiens Q6ZT21
Y2H Prey Pooling
32296183
Intra
LEMD1 Q68G75 TMPPE Homo sapiens Q6ZT21
Validated Y2H
32296183
Intra
LEMD1 Q68G75 ZDHHC15 Homo sapiens Q96MV8
Y2H Prey Pooling
32296183
Intra
LEMD1 Q68G75 ZDHHC15 Homo sapiens Q96MV8
Validated Y2H
32296183
Intra
LEMD1 Q68G75 ZDHHC15 Homo sapiens Q96MV8
Y2H Array
32296183
Intra
LEMD1 Q68G75 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra
LEMD1 Q68G75 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra
LEMD1 Q68G75 ERMAP Homo sapiens Q96PL5
Validated Y2H
32296183
Intra
LEMD1 Q68G75 ERMAP Homo sapiens Q96PL5
Y2H Prey Pooling
32296183
Intra
LEMD1 Q68G75 ERMAP Homo sapiens Q96PL5
Y2H Array
32296183
Intra
LEMD1 Q68G75 MEOX2 Homo sapiens Q6FHY5
Validated Y2H
32296183
Intra
LEMD1 Q68G75 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra
LEMD1 Q68G75 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra
LEMD1 Q68G75 SCN3B Homo sapiens Q9NY72
Y2H Prey Pooling
32296183
Intra
LEMD1 Q68G75 SCN3B Homo sapiens Q9NY72
Validated Y2H
32296183
Intra
LEMD1 Q68G75 SCN3B Homo sapiens Q9NY72
Y2H Array
32296183
Intra
LEMD1 Q68G75 BLCAP Homo sapiens P62952
Y2H Array
32296183
Intra
LEMD1 Q68G75 BLCAP Homo sapiens P62952
Y2H Prey Pooling
32296183
Intra
LEMD1 Q68G75 EBP Homo sapiens Q15125
Y2H Array
32296183
Intra
LEMD1 Q68G75 EBP Homo sapiens Q15125
Y2H Prey Pooling
32296183
Intra
LEMD1 Q68G75 SLC16A7 Homo sapiens O60669
Y2H Array
32296183
Intra
LEMD1 Q68G75 SLC16A7 Homo sapiens O60669
Y2H Prey Pooling
32296183
Intra
LEMD1 Q68G75 MGST3 Homo sapiens O14880
Y2H Prey Pooling
32296183
Intra
LEMD1 Q68G75 MGST3 Homo sapiens O14880
Y2H Array
32296183
Intra
LEMD1 Q68G75 REEP4 Homo sapiens Q9H6H4
Validated Y2H
32296183
Intra
LEMD1 Q68G75 REEP4 Homo sapiens Q9H6H4
Y2H Prey Pooling
32296183
Intra
LEMD1 Q68G75 REEP4 Homo sapiens Q9H6H4
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS07587 LEMD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus LEMD1 MGD MGI:1922403
Bos taurus LEMD1 VGNC VGNC:30835
Macaca mulatta LEMD1 VGNC VGNC:99999
Felis catus LEMD1 VGNC VGNC:63210
Rattus norvegicus LEMD1 RGD RGD:2322707
Canis familiaris LEMD1 VGNC VGNC:42631
Others LEMD1 NCBI