GTX-758
Based on 1 Customer Validation
GTX-758 is an orally active, nonsteroidal, selective agonist of ERα. GTX-758 plays an important role in castration resistant prostate cancer (CRPC) research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.59%
- CAS. Nr.: 938067-78-8
- Formel: C19H13F2NO3
- Molecular Weight:341.31
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
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ERα |
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS. Nr. 938067-78-8
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Appearance Solid
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Molecular Weight 341.31
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Formel C19H13F2NO3
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Color White to off-white
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SMILES
O=C(N(C1=CC=C(F)C=C1)C2=CC=C(O)C=C2)C3=CC=C(O)C(F)=C3
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Synonyms
Capesaris
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (292.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (282 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9299 mL | 14.6494 mL | 29.2989 mL | 73.2472 mL |
| 5 mM | 0.5860 mL | 2.9299 mL | 5.8598 mL | 14.6494 mL | |
| 10 mM | 0.2930 mL | 1.4649 mL | 2.9299 mL | 7.3247 mL | |
| 15 mM | 0.1953 mL | 0.9766 mL | 1.9533 mL | 4.8831 mL | |
| 20 mM | 0.1465 mL | 0.7325 mL | 1.4649 mL | 3.6624 mL | |
| 25 mM | 0.1172 mL | 0.5860 mL | 1.1720 mL | 2.9299 mL | |
| 30 mM | 0.0977 mL | 0.4883 mL | 0.9766 mL | 2.4416 mL | |
| 40 mM | 0.0732 mL | 0.3662 mL | 0.7325 mL | 1.8312 mL | |
| 50 mM | 0.0586 mL | 0.2930 mL | 0.5860 mL | 1.4649 mL | |
| 60 mM | 0.0488 mL | 0.2442 mL | 0.4883 mL | 1.2208 mL | |
| 80 mM | 0.0366 mL | 0.1831 mL | 0.3662 mL | 0.9156 mL | |
| 100 mM | 0.0293 mL | 0.1465 mL | 0.2930 mL | 0.7325 mL |
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