HOPan
Based on 3 publication(s) in Google Scholar
HOPan is a PanK substrate and Pantothenate (HY-B0430) analog. HOPan inhibits CoA levels.
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- CAS. Nr.: 18679-90-8
- Formel: C10H19NO5
- Molecular Weight:233.26
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Speicherung:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) HOPan
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Biologische Aktivität
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 18679-90-8
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Appearance Oil
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Molecular Weight 233.26
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Formel C10H19NO5
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Color Colorless to light yellow
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SMILES
OCC(C)(C)[C@@H](O)C(NCCCC(O)=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (3)
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Journal Impact Factor
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Most Recent
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Antioxidants (Basel)
2026 May 9;15(5):600. PMID: 42193221 -
Aging Cell
HLH-30/TFEB Rewires the Chaperone Network to Promote Proteostasis Upon Perturbations to the Coenzyme A and Iron-Sulfur Cluster Biosynthesis Pathways. [Abstract]2025 Apr 30:e70038. PMID: 40304211 -
Lösungsmittel & Löslichkeit
H2O : 100 mg/mL (428.71 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Mostert KJ, et al. The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity. ACS Chem Biol. 2021 Nov 19;16(11):2401-2414. [Content Brief]
[2]. Ma Y, et al. Highly selective DNA aptamer sensor for intracellular detection of coenzyme A. Chem Sci. 2025 Mar 28;16(18):8023-8029. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.2871 mL | 21.4353 mL | 42.8706 mL | 107.1765 mL |
| 5 mM | 0.8574 mL | 4.2871 mL | 8.5741 mL | 21.4353 mL | |
| 10 mM | 0.4287 mL | 2.1435 mL | 4.2871 mL | 10.7177 mL | |
| 15 mM | 0.2858 mL | 1.4290 mL | 2.8580 mL | 7.1451 mL | |
| 20 mM | 0.2144 mL | 1.0718 mL | 2.1435 mL | 5.3588 mL | |
| 25 mM | 0.1715 mL | 0.8574 mL | 1.7148 mL | 4.2871 mL | |
| 30 mM | 0.1429 mL | 0.7145 mL | 1.4290 mL | 3.5726 mL | |
| 40 mM | 0.1072 mL | 0.5359 mL | 1.0718 mL | 2.6794 mL | |
| 50 mM | 0.0857 mL | 0.4287 mL | 0.8574 mL | 2.1435 mL | |
| 60 mM | 0.0715 mL | 0.3573 mL | 0.7145 mL | 1.7863 mL | |
| 80 mM | 0.0536 mL | 0.2679 mL | 0.5359 mL | 1.3397 mL | |
| 100 mM | 0.0429 mL | 0.2144 mL | 0.4287 mL | 1.0718 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
HOPan Related Classifications
HY-139729 Related Classifications
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