Monardic acid A
Monardic acid A is a selective inhibitor of AChE, with an IC50 of 53.1 μM against AChE from electric eel. Monardic acid A shows weak inhibitory activity against human erythrocyte AChE (IC50 >100 μM) and has no significant inhibitory effect on BChE. Monardic acid A reduces acetylcholine breakdown by inhibiting AChE activity, and also exhibits inhibitory activity against histamine release and hyaluronidase, thus exerting anti-inflammatory and neurotransmitter regulatory effects. Monardic acid A can be isolated from lungwort (Pulmonaria officinalis) and thyme (Thymus gobicus), and is mainly used in the development of anti-inflammatory drugs and drugs related to neurodegenerative diseases.
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- CAS. Nr.: 1607436-76-9
- Formel: C27H22O12
- Molecular Weight:538.46
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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AChE |
Chemical Information
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CAS. Nr. 1607436-76-9
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Molecular Weight 538.46
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Formel C27H22O12
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SMILES
OC([C@@H]1C2=C(/C=C/C(O[C@@H](C(O)=O)CC3=CC(O)=C(C=C3)O)=O)C=CC(O)=C2O[C@H]1C4=CC(O)=C(C=C4)O)=O
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
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Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Monardic acid A Related Classifications
HY-N16715 Related Classifications
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