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NADH-IN-3

NADH-IN-3 (Compound C4-1) is a NADH inhibitor with a MIC of 4 μg/mL (13.042 μM) for type II NADH dehydrogenase of Mycobacterium tuberculosis (Mtb). NADH-IN-3 significantly interrupts ATP synthesis, shows potent inhibitory effects against mono (Rifampicin (HY-B0272) and Isoniazid (HY-B0329)) and multi drug-resistant (Mtb) strains and an anti-bactericidal activity against HepG2 cells with low cytotoxicity (SI: 16.52).

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  • Formel: C15H18N2OS2
  • Molecular Weight:306.45
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • NADH-IN-3 Chemical Structure
    NADH-IN-3 Chemical Structure
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  • NADH-IN-3 Chemical Structure
    NADH-IN-3 Chemical Structure
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  • NADH-IN-3