Napyradiomycin A1
Napyradiomycin A1 is one enantioselective compound of napyradiomycins. napyradiomycins are an intriguing family of halogenated natural products with activity against several tumor cell lines as well as some bacterial strains.
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- CAS. Nr.: 103106-24-7
- Formel: C25H30Cl2O5
- Molecular Weight:481.41
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HUVEC | GI50 |
27.6 μM
Compound: 1
|
Antiproliferative activity against HUVEC after 72 hrs by Celltiter-Glo luminescent cell viability assay
Antiproliferative activity against HUVEC after 72 hrs by Celltiter-Glo luminescent cell viability assay
|
[PMID: 28749137] |
| HUVEC | IC50 |
10 μM
Compound: 1
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Antiangiogenic activity in HUVEC assessed as inhibition of VEGF-induced tube formation after 24 hrs by calcein-AM dye based fluorescence assay
Antiangiogenic activity in HUVEC assessed as inhibition of VEGF-induced tube formation after 24 hrs by calcein-AM dye based fluorescence assay
|
[PMID: 28749137] |
Chemical Information
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CAS. Nr. 103106-24-7
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Molecular Weight 481.41
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Formel C25H30Cl2O5
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SMILES
C/C(CC/C=C(C)/C)=C\C[C@@](C(C1=CC(O)=CC(O)=C21)=O)(OC3(C)C)[C@@](C2=O)(C[C@H]3Cl)Cl
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Structure Classification
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Initial Source
Chainia rubra
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)