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Art. -Nr.: HY-187147

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NMDAR modulator 3

NMDAR modulator 3 is a subunit-selective NMDA receptor potentiator targeting NMDAR receptors containing NR2C/NR2D subunits. NMDAR modulator 3 can be used for the research of schizophrenia, parkinson's disease, cognitive disorders, depression, neuropathic pain, stroke, traumatic brain injury, epilepsy, neurodegeneration.

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CAS. Nr.: 342379-28-6
Formel: C₂₃H₂₃NO₄S
Molecular Weight:409.50

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Please store the product under the recommended conditions in the Certificate of Analysis.

NMDAR modulator 3 Chemical Structure

CAS. Nr.: 342379-28-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
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- IC₅₀ & Target
- In Vitro
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Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]

NR2C

NR2D

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In Vitro

NMDAR modulator 3 (compound 1481) (100 μM) exerts mild potentiating effects of 113% and 119% on NR1/NR2C and NR1/NR2D receptors, respectively, and shows no significant activity against other glutamate receptors (97%)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 342379-28-6
Molecular Weight 409.50
Formel C₂₃H₂₃NO₄S
SMILES

O=C(O)C1=C(SC=C1C=2C=CC(OC)=CC2)NC(=O)C3=CC=C(C=C3)C(C)(C)C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Traynelis SF, Liotta DC, Santangelo RM, Garnier FE. Subunit selective NMDA receptor potentiators for the treatment of neurological conditions. WO2010088414 A2. 2010 Aug 5.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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NMDAR modulator 3

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Biologische Aktivität

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Help & FAQs

NMDAR modulator 3 Related Classifications

HY-187147 Related Classifications