CD83
CD83 is a type I transmembrane glycoprotein of the immunoglobulin superfamily that serves as the classic marker of dendritic cell maturation. Its expression is low on immature precursors and rises sharply upon activation, and the protein also reaches the surface of activated B cells and subsets of T cells. The extracellular IgV-like domain can be shed as a soluble CD83 form that exerts immunosuppressive effects, whereas membrane CD83 supports antigen presentation and is required for efficient CD4+ T cell priming. Because of its specificity for mature professional antigen-presenting cells, CD83 is widely used to monitor dendritic cell vaccines and activation status in immune monitoring assays.
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CD83 Recombinant Proteins (8)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
