TYRO3
TYRO3 (also known as Sky, Brt, or Dtk) is one of the three TAM receptor tyrosine kinases alongside Axl and Mer. Its extracellular region contains two immunoglobulin-like domains followed by two fibronectin type III domains, and its ligands are the vitamin K-dependent proteins Gas6 and PROS1 presented on apoptotic cell surfaces. TYRO3 signaling supports apoptotic cell clearance, myelination in the nervous system, natural killer cell homeostasis, and dendritic cell tolerance through induction of SOCS proteins. Among TAM members, TYRO3 is distinguished by its prominent expression in neurons, glia, and lymphoid cells, and by reported roles as an entry cofactor for enveloped viruses and a modifier of autoimmune and neurodegenerative disease models.
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TYRO3 Recombinant Proteins (5)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
