Resolvin D2 methyl ester
Resolvin D2 methyl ester is an ester derivative of the DHA (HY-B2167) metabolite Resolvin D2 (HY-121636) with anti-inflammatory and anti-infective activities. Resolvin D2 is a leukocyte modulator and a potent inhibitor of neuronal TRPV1 (IC50=0.1 nM) and TRPA1 (IC50=2 nM). Resolvin D2 can be used in sepsis research.
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- CAS. Nr.: 810668-53-2
- Formel: C23H34O5
- Molecular Weight:390.51
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Chemical Information
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CAS. Nr. 810668-53-2
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Molecular Weight 390.51
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Formel C23H34O5
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SMILES
CC/C=C\C[C@H](O)[C@H](O)/C=C/C=C/C=C\C=C\[C@@H](O)C/C=C\CCC(OC)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Siddiqui YD, et al. Resolvin D2 Induces Resolution of Periapical Inflammation and Promotes Healing of Periapical Lesions in Rat Periapical Periodontitis. Front Immunol. 2019 Feb 26;10:307. [Content Brief] [Content Brief]
[2]. Spite M, et al. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Nature. 2009 Oct 29;461(7268):1287-91. [Content Brief] [Content Brief]
[3]. Park CK, et al. Resolvin D2 is a potent endogenous inhibitor for transient receptor potential subtype V1/A1, inflammatory pain, and spinal cord synaptic plasticity in mice: distinct roles of resolvin D1, D2, and E1.6. J Neurosci. 2011 Dec 14;31(50):18433-8. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)