(RXR)4XB
(RXR)4XB is a cell-penetrating peptide, that binds the phosphorodiamidate morpholino oligomers (PMOs), forms peptide-conjugated PMOs (PPMOs), and improves the delivery of PMO into bacterial cells. (RXR)4XB-PMO conjugate prevents the formation of biofilms, inhibits Pseudomonas aeruginosa with MIC50 of 0.5 to 16 μM, and reduces the bacterial burden in mouse acute pneumonia models.
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- CAS. Nr.: 879010-15-8
- Formel: C81H158N38O15
- Molecular Weight:1904.37
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 879010-15-8
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Molecular Weight 1904.37
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Formel C81H158N38O15
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Sequence
Arg-{Ahx}-Arg-Arg-{Ahx}-Arg-Arg-{Ahx}-Arg-Arg-{Ahx}-Arg-{Ahx-βAla}
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Sequence Shortening
R-{Ahx}-RR-{Ahx}-RR-{Ahx}-RR-{Ahx}-R-{Ahx-βAla}
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
(RXR)4XB Related Classifications
HY-P10559 Related Classifications
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