SM27
SM27 (NSC 37204) is an inhibitor for fibroblast growth factors (FGF). SM27 inhibits angiogenesis through block of FGF2/HSPGs/FGFR1 complex formation.
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- CAS. Nr.: 6266-54-2
- Formel: C21H16N2O9S2
- Molecular Weight:504.49
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
In Vitro
SM27 (0-100 μM, 2 h) inhibits FGF2/heparin and FGF2/ FGFR1 interaction in a dose-dependent way with IC50s of 3.5 and 4 mM, through inhibition of FGF2-mediated cell-cell adhesion with IC50 of 1 mM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 6266-54-2
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Molecular Weight 504.49
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Formel C21H16N2O9S2
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SMILES
O=S(C1=CC(O)=C2C=C(C=CC2=C1)NC(NC3=CC=C4C=C(C=C(C4=C3)O)S(=O)(O)=O)=O)(O)=O
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Synonyms
NSC 37204
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
SM27 Related Classifications
HY-123453 Related Classifications
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