TDPAM02
TDPAM02 is a positive allosteric modulator of AMPA receptor GluA2. TDPAM02 can specifically bind to the ligand-binding domain (LBD) of GluA2 and shows an IC50 of 1.4 nM for the GluA2 flop subtype. TDPAM02 can stabilize the activated conformation of GluA2 receptors, delay the receptor deactivation or desensitization process, maintaining the rapid excitatory synaptic transmission in the central nervous system.
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- CAS. Nr.: 2231101-34-9
- Formel: C22H26N4O4S2
- Molecular Weight:474.59
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
AMPA Receptor |
Chemical Information
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CAS. Nr. 2231101-34-9
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Molecular Weight 474.59
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Formel C22H26N4O4S2
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SMILES
O=S1(=O)NCN(C2=CC(=CC=C21)CCC3=CC=C4C(=C3)N(CNS4(=O)=O)C5CC5)C6CC6
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
TDPAM02 Related Classifications
HY-165475 Related Classifications
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