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Art. -Nr.: HY-14721S1

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Tepotinib-d₃

Name: Tepotinib-d3
Brand: MedChemExpress
SKU: HY-14721S1
Availability: PreOrder

(Synonyms: EMD-1214063-d₃)

Tepotinib-d₃ (EMD-1214063-d₃) is the deuterated-labeled Tepotinib (HY-14721). Tepotinib (EMD-1214063) is an orally active and highly selective, reversible, ATP-competitive c-Met inhibitor with an IC₅₀ of 3 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib inhibits c-Met phosphorylation and induces autophagy. Tepotinib has antitumor effects.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₂₉H₂₅D₃N₆O₂
Molecular Weight:495.59

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Tepotinib-d₃ Chemical Structure

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Biologische Aktivität
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- In Vitro
- Anwendung
Chemical Information
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Bioz

Biologische Aktivität

Beschreibung

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Anwendung

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled CAS 1100598-32-0
Molecular Weight 495.59
Formel C₂₉H₂₅D₃N₆O₂
SMILES

N#CC1=CC=CC(C(C=CC2=O)=NN2CC3=CC=CC(C4=NC=C(C=N4)OCC5CCN(CC5)C([2H])([2H])[2H])=C3)=C1
Synonyms

EMD-1214063-d₃
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.