Ethylnotopterol
Ethylnotopterol is a coumarin found in the roots and rhizomes of Notopterygium incisum and an inhibitor with an IC50 value of 18.1 μM for LPS-induced nitric oxide production. Ethylnotopterol blocks LPS-induced nitric oxide production in macrophage cells.
For research use only. We do not sell to patients.
- CAS No.: 158269-48-8
- Formula: C23H26O5
- Molecular Weight:382.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Ethylnotopterol (compound 13) moderately inhibits LPS-induced nitric oxide production in RAW 264.7 cells with an IC50 of 18.1 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 158269-48-8
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Molecular Weight 382.45
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Formula C23H26O5
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SMILES
C/C(C)=C/C(OCC)C/C(C)=C/COC1=C(C=CO2)C2=CC(O3)=C1C=CC3=O
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ethylnotopterol Related Classifications
HY-N20742 Related Classifications
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