Tilbroquinol
Based on 1 publication(s) in Google Scholar
Tilbroquinol is an orally active halogenated hydroxyquinoline antiprotozoal agent, mainly used for anti-amoebic infections. Tilbroquinol targets intestinal protozoa and Entamoeba histolytica to eliminate parasites in the intestinal lumen. Tilbroquinol can be used in research related to intestinal infections, intestinal amoebiasis and hepatic amoebiasis.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 98.02%
- CAS No.: 7175-09-9
- Formule: C10H8BrNO
- Masse moléculaire:238.08
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Drug-Induced Liver Injury (DILI) Compound Library
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Antiparasitic Compound library
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Heterocyclic Compound Library
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Multi-Target Compound Library
HY-L176
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Bioactive Compound Library Max
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MCE Bioactive Compound Library
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Bioactive Compound Library
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High-Throughput Bioactive Compound Library
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Anti-Infection Compound Library
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Publications Citing Use of MedChemExpress (MCE) Tilbroquinol
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Activité biologique
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Amebae |
Tilbroquinol is associated with severe subacute myelo-optic neuropathy (SMON, characterized by numbness of lower limbs, paralysis, optic atrophy and even blindness)[1]
Tilbroquinol is often formulated into a compound preparation with Tiliquinol (HY-W018397) for the study of intestinal infections[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 7175-09-9
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Appearance Solid
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Masse moléculaire 238.08
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Formule C10H8BrNO
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Color Light yellow to yellow
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SMILES
OC1=C2N=CC=CC2=C(C)C=C1Br
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (1)
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Journal Impact Factor
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Most Recent
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Anal Chem
Exposome-Scale Investigation of Cl-/Br-Containing Chemicals Using High-Resolution Mass Spectrometry, Multistage Machine Learning, and Cloud Computing. [Abstract]2025 Jun 3;97(21):11099-11109. PMID: 40401576
Solvant et solubilité
DMSO : ≥ 50 mg/mL (210.01 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Pureté et documentation
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Fiche technique (297 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2003 mL | 21.0013 mL | 42.0027 mL | 105.0067 mL |
| 5 mM | 0.8401 mL | 4.2003 mL | 8.4005 mL | 21.0013 mL | |
| 10 mM | 0.4200 mL | 2.1001 mL | 4.2003 mL | 10.5007 mL | |
| 15 mM | 0.2800 mL | 1.4001 mL | 2.8002 mL | 7.0004 mL | |
| 20 mM | 0.2100 mL | 1.0501 mL | 2.1001 mL | 5.2503 mL | |
| 25 mM | 0.1680 mL | 0.8401 mL | 1.6801 mL | 4.2003 mL | |
| 30 mM | 0.1400 mL | 0.7000 mL | 1.4001 mL | 3.5002 mL | |
| 40 mM | 0.1050 mL | 0.5250 mL | 1.0501 mL | 2.6252 mL | |
| 50 mM | 0.0840 mL | 0.4200 mL | 0.8401 mL | 2.1001 mL | |
| 60 mM | 0.0700 mL | 0.3500 mL | 0.7000 mL | 1.7501 mL | |
| 80 mM | 0.0525 mL | 0.2625 mL | 0.5250 mL | 1.3126 mL | |
| 100 mM | 0.0420 mL | 0.2100 mL | 0.4200 mL | 1.0501 mL |
Tilbroquinol Related Classifications
HY-15537 Related Classifications
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