AB13-08
AB13-08 is a selective dopamine receptor agonist with a Ki value of 53.9 nM for human D3R. AB13-08 is applicable to the research of neurological disorders such as Parkinson's disease and schizophrenia.
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- Formule: C24H31N7O2
- Masse moléculaire:449.55
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Activité biologique
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Human D3 Receptor 53.9 nM (Ki) |
Human D2 Receptor 2690 nM (Ki) |
AB13-08 (compound 4b) (90 min) binds to human D3 receptors expressed in HEK293 cells with a Ki value of 53.9 nM, and exhibits 49.9-fold binding selectivity over human D2 receptors (with a Ki value of 2690 nM)[1].
AB13-08 acts as a full agonist on human D3 receptors expressed in HEK293T cells, with a potency of 1.10 nM, and exhibits over 2800-fold potency selectivity over human D2 receptors[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 449.55
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Formule C24H31N7O2
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SMILES
NC1=NC=C(C=C1)[C@H]2CN([C@H](CO2)C)CCCCNC(C3=CC(C)=CC=C3N4N=CC=N4)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AB13-08 Related Classifications
HY-184588 Related Classifications
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