BIM5078
BIM5078 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that can inhibit the expression of known HNF4α target genes. BIM5078 represses insulin promoter activity through HNF4α antagonism. BIM5078 can be used for the research of cancer and diabetes.
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- CAS No.: 337506-43-1
- Formule: C14H10ClN3O4S
- Masse moléculaire:351.76
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Voir tous les produits spécifiques à Isoform Nuclear Hormone Receptor 4A/NR4A
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Activité biologique
hepatocyte nuclear factor 4α (HNF4α)[1]
BIM5078 (0.63-5μM; 48 h) inhibits the expression of endogenous insulin in T6PNE cells with IC50 value of 930 nM[1].
BIM5078 (2.5-10 μM; 5-48 h) inhibits HNF4α gene expression in HepG2 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 337506-43-1
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Masse moléculaire 351.76
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Formule C14H10ClN3O4S
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SMILES
[O-][N+](C1=CC=C(C(S(=O)(N2C3=C(N=C2C)C=CC=C3)=O)=C1)Cl)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BIM5078 Related Classifications
HY-119971 Related Classifications
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