Biphalin TFA
Biphalin TFA, a BBB-penetrable opioid peptide analog, contains two active enkephalin pharmacophores. Biphalin TFA has high affinity for opioid receptors. Biphalin TFA shows analgesic effect in acute, neuropathic, and chronic animal pain models. Biphalin TFA is also an antiviral, antiproliferative, anti-inflammatory, and neuroprotective agent.
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- CAS No.: 126872-95-5
- Formule: C46H56N10O10·xC2HF3O2
- Masse moléculaire:909.00 (free base)
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Chemical Information
-
CAS No. 126872-95-5
-
Masse moléculaire 909.00 (free base)
-
Formule C46H56N10O10·xC2HF3O2
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Sequence
Tyr-{dAla}-Gly-Phe-NH2 (covalent bridge:Phe-Phe, dimer)
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Sequence Shortening
Y-{D-Ala}-GF-NH2 (covalent bridge:Phe-Phe, dimer)
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. T J Abbruscato, et al. Blood-to-central nervous system entry and stability of biphalin, a unique double-enkephalin analog, and its halogenated derivatives. J Pharmacol Exp Ther. 1996, 276,3. [Content Brief]
[2]. Redkiewicz P, et al. Biphalin-A Potent Opioid Agonist-As a Panacea for Opioid System-Dependent Pathophysiological Diseases? Int J Mol Sci. 2021 Oct 21;22(21):11347. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Biphalin TFA Related Classifications
HY-P3223 Related Classifications
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