CCL-34
CCL-34 is a Toll-like receptor 4 (TLR4) activator. CCL-34 significantly induced dendritic cell (DC) CD83 expression and IL-12p70 production in a dose-dependent manner, thereby inducing DC maturation. CCL-34 enhanced the allostimulatory activity of DC on naive CD4+CD45+RA+ T cell proliferation and IFN-γ secretion. CCL-34 further induced antigen presentation ability in mice inoculated with doxorubicin-treated colorectal cancer cells. CCL-34 can be used in studies of immune stimulation.
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- CAS No.: 943316-60-7
- Formule: C32H62N2O8
- Masse moléculaire:602.84
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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TLR4 |
Chemical Information
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CAS No. 943316-60-7
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Masse moléculaire 602.84
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Formule C32H62N2O8
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SMILES
CCCCCCCCCCCNC([C@@H](NC(CCCCCCCCCCC)=O)CO[C@H]1O[C@@H]([C@@H]([C@@H]([C@H]1O)O)O)CO)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)