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Cat. No.: HY-117767

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CZ830

CZ830 is a mTOR kinase inhibitor with an IC₅₀ of < 1 μM. CZ830 is applicable to the research of collagen-induced arthritis.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 1333108-58-9
Formule: C₂₅H₂₆F₃N₅O₄S
Masse moléculaire:549.57

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CZ830 Chemical Structure

CAS No.: 1333108-58-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

CZ830 is a mTOR kinase inhibitor with an IC₅₀ of < 1 μM. CZ830 is applicable to the research of collagen-induced arthritis^[1].

Voir tous les produits spécifiques à Isoform mTOR :

In Vitro

CZ830 inhibits mTOR kinase activity with an IC₅₀ of <1 μM, forming specific hydrogen bonds with key mTOR residues Asp2195, Asp2357, and Val2240^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1333108-58-9
Masse moléculaire 549.57
Formule C₂₅H₂₆F₃N₅O₄S
SMILES

S(C)(=O)(=O)C1=C(C2=NC(=NC(=C2)C3=CC=C(NC(NCC(F)F)=O)C=C3)N4[C@@H](C)COCC4)C=C(F)C=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Xu T, et al. Targeting mTOR for fighting diseases: A revisited review of mTOR inhibitors. Eur J Med Chem. 2020;199:112391. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références

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CZ830

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