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Disitamab

(Synonyms: RC48-0)
1 Cited Publications
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Based on 1 publication(s) in Google Scholar

Disitamab (RC48-0) is a humanized monoclonal antibody targeting HER2. Disitamab can be used in the synthesis of antibody-drug conjugates (ADCs), Disitamab vedotin (HY-P9985).

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  • Pureté: 98.73%
  • CAS No.: 2185868-98-6
  • Masse moléculaire:144.16 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Disitamab
  • Experimental Validation Results for Disitamab
  • Experimental Validation Results for Disitamab
  • Disitamab Chemical Structure
    Disitamab Chemical Structure
CAS No.: 2185868-98-6
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized HER2/CD340 Protein, Human can bind Disitamab. The EC50 for this effect is 5.697 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 MCF-7 cells with Disitamab (HY-P99854, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Disitamab Chemical Structure
    1/16
  • Disitamab
  • Immobilized HER2/CD340 Protein, Human can bind Disitamab. The EC50 for this effect is 5.697 ng/mL.
  • Flow cytometric analysis of 1X106 MCF-7 cells with Disitamab (HY-P99854, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).