E 3040
E 3040 is an orally active dual inhibitor of 5-lipoxygenase and thromboxane synthase. E 3040 exhibits anti-inflammatory effect.
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- CAS No.: 145096-30-6
- Formule: C16H17N3OS
- Masse moléculaire:299.39
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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5-Lipoxygenase |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RBL-1 | IC50 |
0.23 μM
Compound: 26a
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Tested for inhibitory activity against 5-lipoxygenase in microsome of RBL-1 cells
Tested for inhibitory activity against 5-lipoxygenase in microsome of RBL-1 cells
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[PMID: 7932529] |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:LPS (HY-D1056)-treated rats[1]
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Dosage:30 and 100 mg/kg
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Administration:Orally administration
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Result:Inhibited the increase in vascular permeability.
Inhibited the production of leukotriene B(4) and thromboxane B(2).
Increased the production of prostaglandin E(2).
Chemical Information
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CAS No. 145096-30-6
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Masse moléculaire 299.39
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Formule C16H17N3OS
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SMILES
OC1=C(C)C(CC2=CC=CN=C2)=C3N=C(NC)SC3=C1C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
E 3040 Related Classifications
HY-105193 Related Classifications
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