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Faricimab

(Synonyms: RG7716; RO-6867461)
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Based on 1 Customer Validation

Faricimab, an overall good safety and tolerability profile, is a bispecific antibody targeting Angiopoietin-2 (Ang-2) and vascular endothelial growth factor-A (VEGF-A). Faricimab prevents retinal vascular leakage, cell death and inflammation in retinal ischemia/reperfusion (I/R) injury and sCNV mouse models. Faricimab demonstrates statistically superior visual acuity gains versus Ranibizumab (HY-P9951). Faricimab can be used for retinal diseases, such as age-related macular degeneration (w-AMD), diabetic macular edema (DME) and macular edema following retinal vein occlusion (RVO).

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  • Pureté: 97.97%
  • CAS No.: 1607793-29-2
  • Masse moléculaire:146.16 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Faricimab
  • Experimental Validation Results for Faricimab
  • Experimental Validation Results for Faricimab
  • Experimental Validation Results for Faricimab
  • Faricimab Chemical Structure
    Faricimab Chemical Structure
CAS No.: 1607793-29-2
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Faricimab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG1-kappa-lambda with half-IG VL-CH1/VH-CK crossover

  • 1/16

    Immobilized Faricimab can bind VEGF165 Protein, Human.The EC50 for this effect is 3.418 ng/mL.

  • 1/16

    Immobilized Faricimab can bind Human Angiopoietin-2/ANGPT2 Protein (His Tag).The EC50 for this effect is 4.10 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 HeLa cells with Faricimab (HY-P99116, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control.

  • Faricimab Chemical Structure
    1/16
  • Faricimab
  • Immobilized Faricimab can bind VEGF165 Protein, Human.The EC50 for this effect is 3.418 ng/mL.
  • Immobilized Faricimab can bind Human Angiopoietin-2/ANGPT2 Protein (His Tag).The EC50 for this effect is 4.10 ng/mL.
  • Flow cytometric analysis of 1X106 HeLa cells with Faricimab (HY-P99116, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control.
  • IgG1-kappa-lambda with half-IG VL-CH1/VH-CK crossover