FFA2 agonist-2
FFA2 agonist-2 is a potent agonist of the FFA2 (GPR43) receptor, with a pEC50 of 7.9 for human FFA2, and a pEC50 of 7.3 for murine FFA2. FFA2 agonist-2 acts as an orthosteric agonist and shows no obvious cross‑activity against FFA1, FFA3 and FFA4. FFA2 agonist-2 can be used for FFA2 receptor research in type 2 diabetes and metabolic disorders.
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- CAS No.: 1229363-11-4
- Formule: C23H20Cl2N2O3S
- Masse moléculaire:475.39
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
IC50 & Target
[1]|
FFAR2 7.9 (pEC50, 人源) |
FFAR2 7.3 (pEC50, 鼠源) |
In Vitro
FFA2 agonist-2 (compound 8) acts as a potent agonist at both hFFA2 and mFFA2 receptors in CHO cells, with a pEC50 of 7.9 (hFFA2) and 7.3 (mFFA2), and binds to hFFA2 with a pKi of 6.7[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Parmacokinetics
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1229363-11-4
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Masse moléculaire 475.39
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Formule C23H20Cl2N2O3S
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SMILES
OC(C[C@@H](CC1=CC=CC=C1)C(N(C2CC2)C3=NC(C4=C(C=CC(Cl)=C4)Cl)=CS3)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FFA2 agonist-2 Related Classifications
HY-182729 Related Classifications
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