ICSN3250
ICSN3250 is a halitulin analogue and specific mTORC1 inhibitor. ICSN3250 directly binds to mTOR's FRB domain and displaces phosphatidic acid (PA), reversing mTORC1 activation. ICSN3250 shows high cytotoxicity in cancer cells (nanomolar concentration) through a caspase-independent cell death mechanism. ICSN3250 specifically inhibits the mTORC1 pathway, inducing autophagy and G0-G1 cell-cycle arrest in cancer cells. ICSN3250 can be used for the study of cancer.
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- CAS No.: 1561902-73-5
- Formule: C31H40N4O8
- Masse moléculaire:596.67
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 1561902-73-5
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Masse moléculaire 596.67
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Formule C31H40N4O8
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SMILES
OC1=CC(C2=CN(CCCN3CCCCCCCCCCCC3)C=C2C4=CC([N+]([O-])=O)=C(O)C(O)=C4)=CC([N+]([O-])=O)=C1O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ICSN3250 Related Classifications
HY-112774 Related Classifications
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