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Cat. No.: HY-U00085

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Itameline

Name: Itameline
Brand: MedChemExpress
SKU: HY-U00085
Price: 490.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: RU 47213)

Itameline (RU 47213) is a prodrug with oral and long-lasting cholinergic activity. Itameline is a novel tetrahydropyridine-oxime that is cleaved in vivo to form an active metabolite, RU 35963. RU 35963 is a muscarinic receptor agonist that is nonselective with respect to receptor subtypes. Itameline possesses the capacity to reduce memory deficits induced by an impairment of cholinergic transmission in the rat.

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CAS No.: 145071-44-9
Formule: C₁₄H₁₅ClN₂O₃
Masse moléculaire:294.73

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Itameline Chemical Structure

CAS No.: 145071-44-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Voir tous les produits spécifiques à Isoform Cholinesterase (ChE) :

AChE
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Chemical Information

CAS No. 145071-44-9
Masse moléculaire 294.73
Formule C₁₄H₁₅ClN₂O₃
SMILES

O=C(N1CCC=C(/C=N/OC)C1)OC2=CC=C(Cl)C=C2
Synonyms

RU 47213
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. M M'Harzi, et al. Ameliorating effects of RU 47213, a novel oral and long-lasting cholinomimetic agent, on working memory impairments in rats. Pharmacol Biochem Behav. 1997 Apr;56(4):663-8. [Content Brief]

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1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Itameline

Voir tous les produits spécifiques à Isoform Cholinesterase (ChE)