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Cat. No.: HY-183459

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LB 11058

LB 11058 is a Cephalosporin Antibacterial agent. LB 11058 inhibits the growth of pathogenic bacteria, including multidrug-resistant staphylococci and streptococci, but shows weak activity against Enterococcus faecium, Corynebacterium species, Enterobacteriaceae and non-fermenting Gram-negative bacilli. LB 11058 can be used in bacterial infection research.

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CAS No.: 591207-81-7
Formule: C₁₈H₁₅ClN₈O₆S₃
Masse moléculaire:571.01

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Please store the product under the recommended conditions in the Certificate of Analysis.

LB 11058 Chemical Structure

CAS No.: 591207-81-7

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Activité biologique
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- In Vitro
Chemical Information
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Activité biologique

Description

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In Vitro

LB 11058 (0.008-64 μg/mL) exhibits potent in vitro activity against most tested Gram-positive isolates, with MIC₉₀ values ≤1 μg/mL for β-hemolytic streptococci, penicillin-susceptible/resistant viridans streptococci, Oxacillin (HY-B0925A)-susceptible/resistant S. aureus, Oxacillin-susceptible/resistant coagulase-negative staphylococci (CoNS), vancomycin (HY-B0671)-nonsusceptible staphylococci, and Vancomycin-susceptible/resistant E. faecalis; it shows weak activity against E. faecium, Enterococcus spp., Bacillus spp., and Corynebacterium spp.^[1]

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 591207-81-7
Masse moléculaire 571.01
Formule C₁₈H₁₅ClN₈O₆S₃
SMILES

OC(C1=C(/C=C/SC2=CC(N=C(N2)N)=O)CS[C@@]([C@@H]3NC(/C(C4=C(SC(N)=N4)Cl)=N\O)=O)([H])N1C3=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Sader HS, et al. In vitro activities of the novel cephalosporin LB 11058 against multidrug-resistant Staphylococci and Streptococci. Antimicrobial agents and chemotherapy. 2004 Jan;48(1):53-62. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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LB 11058

Voir tous les produits spécifiques à Isoform Antibiotic

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

LB 11058 Related Classifications

HY-183459 Related Classifications