Luffariellolide
Luffariellolide is an inhibitor of human synovial fluid phospholipase A2 (HSF-PLA2) (IC50=5 μM). Luffariellolide effectively inhibits phorbol ester (PMA)-induced ear edema (ED50=50 μg/ear).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 111149-87-2
- Formule: C25H38O3
- Masse moléculaire:386.57
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Voir tous les produits spécifiques à Isoform Phospholipase
More
Activité biologique
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| L5178Y | ED50 |
3.3 μg/mL
Compound: 6
|
Cytotoxicity against mouse L5178Y cells by MTT assay
Cytotoxicity against mouse L5178Y cells by MTT assay
|
[PMID: 15568767] |
| MDA-MB-231 | IC50 |
4.5 μM
Compound: 11
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by SRB assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by SRB assay
|
[PMID: 23944963] |
| T47D | IC50 |
3.6 μM
Compound: 11
|
Inhibition of hypoxia-induced HIF-1 activation in human T47D cells by luciferase reporter gene assay
Inhibition of hypoxia-induced HIF-1 activation in human T47D cells by luciferase reporter gene assay
|
[PMID: 23944963] |
| T47D | IC50 |
5.1 μM
Compound: 11
|
Antiproliferative activity against human T47D cells after 48 hrs by SRB assay
Antiproliferative activity against human T47D cells after 48 hrs by SRB assay
|
[PMID: 23944963] |
Chemical Information
-
CAS No. 111149-87-2
-
Masse moléculaire 386.57
-
Formule C25H38O3
-
SMILES
CC1(CCCC(C)=C1CC/C(C)=C/CC/C(C)=C/CCC2=CC(OC2O)=O)C
-
Structure Classification
-
Initial Source
Palauan sponge
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)