MitTx
Based on 1 Customer Validation
MitTx is a complex formed by MitTx-α and MitTx-β. MitTx is an ASIC1 channel activator with EC50 values of 9.4 and 23 nM for ASIC1a and ASIC1b isoforms, respectively. MitTx is highly selective for ASIC1 isoforms at neutral pH. Under acidic conditions, MitTx greatly enhances proton-evoked ASIC2a channel activation.
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- Pureté: 98%
- Formule: C899H1331N259O271S23
- Masse moléculaire:20840.26
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Stockage:
Sealed storage, away from moisture and light, under nitrogen.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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Appearance Solid
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Masse moléculaire 20840.26
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Formule C899H1331N259O271S23
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Color White to off-white
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Sequence
Chain1: {Pyr}-Ile-Arg-Pro-Ala-Phe-Cys-Tyr-Glu-Asp-Pro-Pro-Phe-Phe-Gln-Lys-Cys-Gly-Ala-Phe-Val-Asp-Ser-Tyr-Tyr-Phe-Asn-Arg-Ser-Arg-Ile-Thr-Cys-Val-His-Phe-Phe-Tyr-Gly-Gln-Cys-Asp-Val-Asn-Gln-Asn-His-Phe-Thr-Thr-Met-Ser-Glu-Cys-Asn-Arg-Val-Cys-His-Gly (Disulfide bridge: Cys7-Cys54; Cys17-Cys41; Cys33-Cys58); Chain2: Asn-Leu-Asn-Gln-Phe-Arg-Leu-Met-Ile-Lys-Cys-Thr-Asn-Asp-Arg-Val-Trp-Ala-Asp-Phe-Val-Asp-Tyr-Gly-Cys-Tyr-Cys-Val-Ala-Arg-Asp-Ser-Asn-Thr-Pro-Val-Asp-Asp-Leu-Asp-Arg-Cys-Cys-Gln-Ala-Gln-Lys-Gln-Cys-Tyr-Asp-Glu-Ala-Val-Lys-Val-His-Gly-Cys-Lys-Pro-Leu-Val-Met-Phe-Tyr-Ser-Phe-Glu-Cys-Arg-Tyr-Leu-Ala-Ser-Asp-Leu-Asp-Cys-Ser-Gly-Asn-Asn-Thr-Lys-Cys-Arg-Asn-Phe-Val-Cys-Asn-Cys-Asp-Arg-Thr-Ala-Thr-Leu-Cys-Ile-Leu-Thr-Ala-Thr-Tyr-Asn-Arg-Asn-Asn-His-Lys-Ile-Asp-Pro-Ser-Arg-Cys-Gln (Disulfide bridge: Cys11-Cys70; Cys25-Cys118; Cys27-Cys43; Cys42-Cys100; Cys49-Cys93; Cys59-Cys86; Cys79-Cys91)
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Sequence Shortening
Chain1: {Pyr}-IRPAFCYEDPPFFQKCGAFVDSYYFNRSRITCVHFFYGQCDVNQNHFTTMSECNRVCHG (Disulfide bridge: Cys7-Cys54; Cys17-Cys41; Cys33-Cys58); Chain2: NLNQFRLMIKCTNDRVWADFVDYGCYCVARDSNTPVDDLDRCCQAQKQCYDEAVKVHGCKPLVMFYSFECRYLASDLDCSGNNTKCRNFVCNCDRTATLCILTATYNRNNHKIDPSRCQ (Disulfide bridge: Cys11-Cys70; Cys25-Cys118; Cys27-Cys43; Cys42-Cys100; Cys49-Cys93; Cys59-Cys86; Cys79-Cys91)
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Sealed storage, away from moisture and light, under nitrogen
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Pureté et documentation
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Fiche technique (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MitTx Related Classifications
HY-P5174 Related Classifications
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