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Cat. No.: HY-120126

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ML378

(Synonyms: CID71710938; JJH-254)

ML378 (CID71710938) is a dual LYPLA1 and LYPLA2 inhibitor, with IC₅₀s of 122 nM and 245 nM respectively. ML378 also shows potent inhibition of ABHD6 (IC₅₀ = 3.15 nM). ML378 can be used for elucidating the patho/physiological roles of the LYPLA1 and LYPLA2.

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CAS No.: 1831135-21-7
Formule: C₂₅H₃₂ClN₅O₆
Masse moléculaire:534.00

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

ML378 Chemical Structure

CAS No.: 1831135-21-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Voir tous les produits spécifiques à Isoform Phospholipase :

Chemical Information

CAS No. 1831135-21-7
Masse moléculaire 534.00
Formule C₂₅H₃₂ClN₅O₆
SMILES

O=C(N1CCC(CCC2=CC=C(Cl)C=C2)CC1)ON(C3=O)C(N4C3CN(C(N5CCOCC5)=O)CC4)=O
Synonyms

CID71710938; JJH-254
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Hulce JJ, et al. An in Vivo Active Carbamate-based Dual Inhibitor of Lysophospholipase 1 (LYPLA1) and Lysophospholipase 2 (LYPLA2) 2013 Dec 9 [Updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.

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Calculateur de molarité

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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ML378

Voir tous les produits spécifiques à Isoform Phospholipase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

ML378 Related Classifications

HY-120126 Related Classifications