NMS-P953
NMS-P953 (compound 28) is an orally active JAK2 inhibitor (IC50=0.008 μM) with antitumor activity.
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- CAS No.: 1403679-33-3
- Formule: C16H11ClF3N5O
- Masse moléculaire:381.74
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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JAK2 0.008 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
1.47 μM
Compound: 28
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Antiproliferative activity against human A2780 cells after 72 hrs by Cell Titer-Glo assay
Antiproliferative activity against human A2780 cells after 72 hrs by Cell Titer-Glo assay
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[PMID: 25009002] |
Chemical Information
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CAS No. 1403679-33-3
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Masse moléculaire 381.74
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Formule C16H11ClF3N5O
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SMILES
O=C(C1=C(C2=CC(C(F)(F)F)=CC=C2Cl)NC(C3=NC(N)=NC=C3)=C1)N
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NMS-P953 Related Classifications
HY-129679 Related Classifications
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