NS-062
NS-062 is an orally active, irreversible targeted covalent inhibitor for EGFR, and exhibits antiproliferative efficacy in drug-resistant double mutated H1975 cell with an IC50 of 0.19 μM. NS-062 exhibits antitumor efficacy in mouse H1975 xenograft model.
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- CAS No.: 2226257-92-5
- Formule: C28H30Cl2F2N6O4
- Masse moléculaire:623.48
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Chemical Information
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CAS No. 2226257-92-5
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Masse moléculaire 623.48
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Formule C28H30Cl2F2N6O4
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SMILES
FC(C=C1)=C(Cl)C=C1NC2=NC=NC3=CC(OCCCN4CCOCC4)=C(NC([C@H]5CCCN5C(C(Cl)F)=O)=O)C=C32
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)