Romazarit
Romazarit (RO 31-3948) is an anti-inflammatory agent with antirheumatic effect. Romazarit exhibits PPARα agonist activity. Romazarit (30 mg/kg) inhibits the development of hindpaw inflammation in an adjuvant arthritis model.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 109543-76-2
- Formule: C15H16ClNO4
- Masse moléculaire:309.74
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
|
PPARα |
Chemical Information
-
CAS No. 109543-76-2
-
Masse moléculaire 309.74
-
Formule C15H16ClNO4
-
SMILES
CC(C)(OCC1=C(C)N=C(C2=CC=C(Cl)C=C2)O1)C(O)=O
-
Synonyms
RO 31-3948
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Bloxham DP, et al. Biologic properties of romazarit (Ro 31-3948), a potential disease-modifying antirheumatic drug. J Pharmacol Exp Ther. 1990 Mar;252(3):1331-40. [Content Brief]
[2]. Pillai AD, et al. Tetra substituted thiophenes as anti-inflammatory agents: exploitation of analogue-based drug design. Bioorg Med Chem. 2005 Dec 15;13(24):6685-92. [Content Brief]
[3]. Clary Clish, et al. Romazarit for treating metabolic diseases. WO2010014771A1.
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)