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Cat. No.: HY-173027

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SPB07935

SPB07935 inhibits the plasmepsin II in Plasmodium falciparum and can be used as an antimalarial agent. SPB07935 regulates the life cycle of P. falciparum, inhibits the growth of Plasmodium strains FcB1 and 3D7 with IC₅₀ of 8 μM and 4.7 μM.

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CAS No.: 634190-75-3
Formule: C₂₂H₁₅N₅O₄S₂
Masse moléculaire:477.52

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

SPB07935 Chemical Structure

CAS No.: 634190-75-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

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Chemical Information

CAS No. 634190-75-3
Masse moléculaire 477.52
Formule C₂₂H₁₅N₅O₄S₂
SMILES

O=[N+]([O-])C1=CN=C(S1)SC2=NN=C(C3=CC=CO3)N2C(C=C4)=CC=C4OCC5=CC=CC=C5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Valiente PA, et al., Discovery of a Noncompetitive Open-Flap Selective Inhibitor of Plasmepsin II with Antiplasmodial Activity. J Chem Inf Model. 2025 Feb 24;65(4):2038-2051. [Content Brief]

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Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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SPB07935

Voir tous les produits spécifiques à Isoform Parasite

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

SPB07935 Related Classifications

HY-173027 Related Classifications

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