Tap1a
Tap1a (Theraphotoxin-Tap1a) is a spider venom peptide that inhibits sodium channels with IC50s of 80 nM and 301 nM against Nav1.7 and Nav1.1, respectively. Tap1a shows analgesic effects.
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- Formule: C174H258N52O55S7
- Masse moléculaire:4182.68
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
IC50: 80 nM (Nav1.7), 301 nM (Nav1.1)[1]
Chemical Information
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Masse moléculaire 4182.68
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Formule C174H258N52O55S7
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Synonyms
Theraphotoxin-Tap1a; TRTX-Tap1a; µ/ω-TRTX-Tap1a
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Sequence
Asp-Asp-Cys-Leu-Gly-Met-Phe-Ser-Ser-Cys-Asp-Pro-Asn-Asn-Asp-Lys-Cys-Cys-Pro-Asn-Arg-Lys-Cys-Ser-Arg-Lys-Asp-Gln-Trp-Cys-Lys-Tyr-Gln-Leu-Trp (Disulfide bridge:Cys3-Cys18, Cys10-Cys23, Cys17-Cys30)
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Sequence Shortening
DDCLGMFSSCDPNNDKCCPNRKCSRKDQWCKYQLW (Disulfide bridge:Cys3-Cys18, Cys10-Cys23, Cys17-Cys30)
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tap1a Related Classifications
HY-P5865 Related Classifications
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