TAS-4
TAS-4 is a potent and selective mGluR4 positive allosteric modulator with significant anti-Parkinson's disease activity. TAS-4 is able to show efficacy when used alone or in combination with l-DOPA. TAS-4 is able to reverse haloperidol-induced spasticity when administered alone. TAS-4 enhances the contralateral rotation behavior induced by l-DOPA in a dose-dependent manner. TAS-4 combined with low-dose l-DOPA shows anti-Parkinson's effects similar to full-dose l-DOPA without exacerbating abnormal motor side effects.
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- CAS No.: 794544-99-3
- Formule: C12H8Cl2N2O
- Masse moléculaire:267.11
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Activité biologique
Chemical Information
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CAS No. 794544-99-3
-
Masse moléculaire 267.11
-
Formule C12H8Cl2N2O
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SMILES
O=C(NC1=CC=C(C=C1Cl)Cl)C2=NC=CC=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TAS-4 Related Classifications
HY-115860 Related Classifications
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