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Cat. No.: HY-128783

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VU0090157

VU0090157 is a positive allosteric modulator (PAM) of the M1 muscarinic acetylcholine receptor (mAChR). VU0090157 increases the affinity of ACh by binding to the allosteric site. VU0090157 can be used in the study of schizophrenia and Alzheimer's disease.

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CAS No.: 312622-77-8
Formule: C₁₉H₂₁N₃O₇
Masse moléculaire:403.39

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

VU0090157 Chemical Structure

CAS No.: 312622-77-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

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Chemical Information

CAS No. 312622-77-8
Masse moléculaire 403.39
Formule C₁₉H₂₁N₃O₇
SMILES

O=C(OC1CCCC1)C2=C(N(C(NC2C3=C(C=C4OCOC4=C3)[N+]([O-])=O)=O)C)C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Marlo J E, et al. Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity[J]. Molecular pharmacology, 2009, 75(3): 577-588. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
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Chemical Information
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Références

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VU0090157

Voir tous les produits spécifiques à Isoform mAChR