CHK1-IN-15
CHK1-IN-15 (compound 9a) is a ATP-kompetitive inhibitor of Checkpoint-Kinase-1 (CHK1) with a 95% binding at 1.0 µM. CHK1-IN-15 is a Chk1 target protein ligand of MA203 (HY-179157). CHK1-IN-15 can be used in cancer-related research.
For research use only. We do not sell to patients.
- Formula: C19H24N6O4
- Molecular Weight:400.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Chk1 |
CHK1-IN-15 (2 μM, 48h) induces DNA damage and apoptosis of MIA PaCa-2 cells.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 400.43
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Formula C19H24N6O4
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SMILES
O=C(NC1=CN=C(C)C=N1)NC2=C(OC[C@H]3OCCNC3)C=C(C(NC)=O)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)