2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. CJ033466

CJ033466 is a novel and selective 5-HT4 receptor partial agonist with an EC50 of 9 nM and has gastroprokinetic effect.

For research use only. We do not sell to patients.

CJ033466 Chemical Structure

CJ033466 Chemical Structure

CAS No. : 519148-48-2

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Based on 1 publication(s) in Google Scholar

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Description

CJ033466 is a novel and selective 5-HT4 receptor partial agonist with an EC50 of 9 nM and has gastroprokinetic effect[1].

IC50 & Target[1]

5-HT4 Receptor

9 nM (EC50)

Molecular Weight

377.91

Formula

C19H28ClN5O
CAS No.
Appearance

Solid

Color

Light yellow to light brown

SMILES

O=C(C1=CC(Cl)=C(N)N2C1=NC(C)=C2)NCC3CCN(CC(C)C)CC3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (132.31 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6461 mL 13.2307 mL 26.4613 mL
5 mM 0.5292 mL 2.6461 mL 5.2923 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6461 mL 13.2307 mL 26.4613 mL 66.1533 mL
5 mM 0.5292 mL 2.6461 mL 5.2923 mL 13.2307 mL
10 mM 0.2646 mL 1.3231 mL 2.6461 mL 6.6153 mL
15 mM 0.1764 mL 0.8820 mL 1.7641 mL 4.4102 mL
20 mM 0.1323 mL 0.6615 mL 1.3231 mL 3.3077 mL
25 mM 0.1058 mL 0.5292 mL 1.0585 mL 2.6461 mL
30 mM 0.0882 mL 0.4410 mL 0.8820 mL 2.2051 mL
40 mM 0.0662 mL 0.3308 mL 0.6615 mL 1.6538 mL
50 mM 0.0529 mL 0.2646 mL 0.5292 mL 1.3231 mL
60 mM 0.0441 mL 0.2205 mL 0.4410 mL 1.1026 mL
80 mM 0.0331 mL 0.1654 mL 0.3308 mL 0.8269 mL
100 mM 0.0265 mL 0.1323 mL 0.2646 mL 0.6615 mL
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CJ033466 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CJ033466519148-48-2CJ 033466CJ-0334665-HT ReceptorSerotonin Receptor5-hydroxytryptamine Receptorgastroprokineticgastrointestinal dysfunctionInhibitorinhibitorinhibit

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