1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. CL2-SN-38

CL2-SN-38 

Cat. No.: HY-126350
Handling Instructions

CL2-SN-38 is a part of the antibody drug conjugate (ADC), can conjugate with the anti-Trop-2-humanized antibody hRS7. The anti-Trop-2 hRS7-CL2A-SN-38 ADC provides significant and specific antitumor effects against a range of human solid tumor types.

For research use only. We do not sell to patients.

CL2-SN-38 Chemical Structure

CL2-SN-38 Chemical Structure

CAS No. : 1036969-20-6

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Description

CL2-SN-38 is a part of the antibody drug conjugate (ADC), can conjugate with the anti-Trop-2-humanized antibody hRS7. The anti-Trop-2 hRS7-CL2A-SN-38 ADC provides significant and specific antitumor effects against a range of human solid tumor types[1].

Molecular Weight

1626.80

Formula

C₈₃H₁₀₇N₁₁O₂₃

CAS No.

1036969-20-6

SMILES

O=C(OCC1=CC=C(NC([[email protected]](CCCCN)NC([[email protected]](CC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN2N=NC(CNC(C3CCC(CN4C(C=CC4=O)=O)CC3)=O)=C2)=O)=O)CC5=CC=CC=C5)=O)=O)C=C1)O[[email protected]](C6=C(CO7)C(N8CC9=C(CC)C%10=CC(O)=CC=C%10N=C9C8=C6)=O)(CC)C7=O

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CL2-SN-38
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