CRBN ligand-356
CRBN ligand-356 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-356 can be linked to a target protein ligand via a linker to form a PROTAC.
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- CAS No.: 2925090-58-8
- Formule: C12H9ClN4O2
- Masse moléculaire:276.68
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
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Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2925090-58-8
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Masse moléculaire 276.68
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Formule C12H9ClN4O2
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SMILES
O=C1NC(=O)CCN1C2=CC=C3N=C(Cl)N=CC3=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)