CRBN ligand-452
CRBN ligand-452 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-452 can be linked to a target protein ligand via a linker to form a PROTAC.
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- CAS No.: 2925086-13-9
- Formule: C13H10N4O3
- Masse moléculaire:270.25
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2925086-13-9
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Masse moléculaire 270.25
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Formule C13H10N4O3
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SMILES
O=CC1=NN=CC=2C=CC(=CC12)N3C(=O)NC(=O)CC3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)